I hate to contradict, but I doubt that it'll be more important than Star Wars or 2001: A Space Odyssey, even if it's excellent. Blade Runner 2049 (Villeneuve's last film) was universally acclaimed, but lost money and really appeals to only sci-fi fans. As good as it is, it's not a very important film. I imagine that Dune will be similar to that and Villeneuve's other sci-fi film, Arrival: critically praised and adored by sci-fi fans, but not make much of a dent in other circles, the box office or pop culture. Villeneuve's films tend to be a little niche, open to interpretation and not highly accessible to mainstream audiences. The total box office for all 7 of his films combined is only $680M. Even Disney's Solo, which was a massive flop, earned more than any of Villeneuve's critically acclaimed films. I just don't see Dune being the massive hit that we all hope that it'll be, but I'd love to be wrong.