I'm skeptical of that working outside of transition, but the "can't be worse" point is fair.
Who'd would you put as the 3rd/4th midfielder. I'd assume you'd have Matic as a more CM dropping to DM in the 4-4-2 diamond, Pogba playing more wide although with freedom to reign. So you'd be looking for someone to more frequently play a right side midfielder, I think Mata would end up getting in the way of the front three, so maybe someone like Herrera or maybe Fellaini to replace some of the size of Lukaku.