I kinda disagree with both of these.
What trophy or record was Lemieux going to get (that he didn't already get) in 1992-93? His stats went nuts during the Pens' 17-game winning streak at the end of the season, which wasn't sustainable. Actually, if you add in his 11 playoff games, he scored 178 points in 71 games, which is probably a more realistic pace for his season. Almost no doubt he would have cracked 200 points, however (same in 1988-89), so too bad about that.
Then, McDavid paced for 87 points in his rookie season, so he might have finished around 3rd in scoring -- which would have been incredible and a slam-dunk Calder -- but I don't think he was hitting 100 points, no matter what.
Some ones that come to mind:
-- I wonder if Bobby Orr missed getting his fourth-straight (and, as it turned out, last) Hart trophy in 1972-73 because of missing 15 games. His pace was for 125 points, just a few behind Esposito for the League-lead. He might have won the scoring title again, and if he'd done so, voters would have had to give him another Hart.
-- Wayne Gretzky might have missed officially winning the Art Ross as a rookie in 1979-80 because he missed 1 game... he needed only 1 point to surpass Dionne in scoring, as it turned out. Gretzky also certainly lost the Art Ross (to Mario) in 1987-88 because of 16 games lost to injury. Had he not missed that 1 and those 16 games, he'd likely have had 9 straight scoring titles for 9 seasons in Edmonton.
-- Crosby clearly lost an Art Ross in 2013. Wasn't he only surpassed in scoring in the last few days of the (short) season, and he missed 12 games?