That's what I'm working on right now. I've noticed somethings are easier because I've gotten use to the gameplay (ie.chasing down the pigeons, and car chases), but man the big guys hit hard....
I never understood the complaints about the piegeons on r/SpiderManPS4. I caught them all in my first playthrough without much difficulty.
But yeah, the big bruisers in the DLC present a legit challenge. Which is fun because by that point I was wildly OP.