reimage repair
If this is the program I'm thinking of its adware/crapware. Most of those "quick fix" PC tools are, especially disk/registry cleaners, all snake oil.
The game is 32 bit and uses a single core and not multi-threaded or optimized in a meaningful way, during periods of intensive shifts from regular season to playoffs or into the offseason the game will become unresponsive and you have to be patient, but it usually doesn't crash or error out. Even on beefy rigs this will happen (unless Riz really re-writes the code base of the game). These periods during the sim are partially self-inflicted due to the amount of detail and realistic league structures we have added into the DB thus the more leagues you select the less stable the game can become.
Lowering your detail level and database size can help with stability.