I wouldn't personally but I think other teams would in a heartbeat. I doubt any of the top 2 pick teams would except a trade since a #1 scoring center is one of the hardest things to find.
I wouldn't because as crazy as it sounds, I am more intrigued by Hanifin and even Werenski than those two centers. I want the Flyers to win a Stanley Cup and not just one but multiple ones. If you look at the last 20 Stanley Cup champions, 16 had hall of fame level defenseman. There have been 5 teams to repeat as champions in the last 20 and 4 of the 5 drafted their hall of fame level defender (Colorado is the only repeater who didn't have a HOF level defender their 1st cup and traded for two their 2nd cup).
In reverse I would do the trade if I had the 1 of the top 2 picks to drop down to 3 maybe 4 depending on how Werenski continues to look. The ransom in picks and prospects would be huge much like the Eric Lindros trade. Eric Lindros's draft in 1991 is the perfect example of my thinking: Eric Lindros 1st overall (no cups), Scott Niedermayer 3rd (4 cups, 3 with the team that drafted him). The 2008 draft is another great example as Stamkos 1st overall, no cups, and Doughty 2 overall with 2 cups so far. Stamkos's Tampa Bay team has only been in the playoffs 2 times since he has been drafted.