Homer, outside of Z, was the Datsyuk's best linemate. The problem was that Homer only had about 2-3 good years of hockey left by the time Babcock put them together. After that Babcock kept him with Datsyuk for too long. To the point that Homer had become a liability (much the same way that he kept Bertuzzi and Cleary in the top 6 for far too long.).. But when he was still playing he was the ultimate 3rd wheel for Datsyuk. He was a great at winning puck battles and cycling, but he was also smart enough to know that he had to get Datsyuk the puck back.
Hossa started the season with Datsyuk and Homer. They had some moments of greatness, but far too many moments of no chemistry. They could still produce some, because they were two talented individuals who could capitalize out of thin air, but they were far too much not on the same page. Datsyuk would go too many shifts without even touching the puck because Hossa would be rushing/attacking individually. It was a waste of Datsyuk basically. Hossa could have done the same thing with anyone.
Around the New Year, Babcock switched Hossa and Franzen. Datsyuk, Franzen, and Holmstrom were dominant and played much better as a unit than Datsyuk/Hossa. Unfortunately, Hossa and Z were even worse than Datsyuk and Hossa. Z and Hossa spent far too much time in the defensive zone some games. Like it was shockingly bad some games. Instead of simply putting Datsyuk and Z back together or putting Datsyuk, Zetterberg, and Hossa all on separate lines, Babcock forced Hossa back with Datsyuk to finish the year out. IMO he outcoached himself. I get the idea of wanting two of the best 2-way centers down the middle, but they were so dominant together and they didn't even get a lick of ice time together at even strength that season until game 5 of the Finals when Datsyuk was hobbled and just returning from his injury.