The post I replied to, as with every post I've replied in that manner to, said Wheeler's game has completely fallen off. That claim doesn't hold to scrutiny so far this season.
Could the CDW line completely fail? Sure, maybe Wheeler throws off the chemistry. But the fact that people are so averse to throwing Wheeler on that line seem to have less to do with chemistry and more to do with a strong dislike of Wheeler.
Someone even said that the line would be less effective because Wheeler is too slow, when he's replacing Svechnikov. Who probably is our slowest skater.