The program has had a marked and long-lasting influence on HBO as well as on television shows in the US and Britain such as Curb Your Enthusiasm, 30 Rock and The Office. The supporting cast includes Janeane Garofalo, Bob Odenkirk, Kathryn Harrold, Scott Thompson and Jeremy Piven.
Regarded as an influential and landmark series, it ranked 38 on TV Guide's 50 Greatest TV Shows of All Time, the only HBO comedy to make the list, and was also included in Time magazine's list of the "100 Best TV Shows of All Time".
The show won 24 major awards, including three Primetime Emmy Awards, five CableACE Awards, four American Comedy Awards, two British Comedy Awards, two Peabody Awards, a BAFTA Award and a Satellite Award. It also received 86 nominations, including 56 Primetime Emmy Awards nominations, five Directors Guild of America nominations, six Writers' Guild of America nominations, six American Comedy Awards nominations, three Golden Globe nominations, three Satellite Awards nominations and a GLAAD Award nomination.