For Nathan MacKinnon or Drouin? Definitely. I would also look to move Edler + for the 3rd overall pick to get both MacKinnon AND Drouin. Of course Milbury wouldn't do that, because he's not a good GM.
Why is this a bad idea? The Canucks have no future first line talent in the organization, and the Sedins aren't players we can build around if we want to go far in the playoffs anymore. Time to move on from them and retool. Hell, those series of deals could probably make us more competitive in 2014-15 than keeping the Sedins would.
I agree that this is the kind of move they *should* do - sadly I don't think Gillis is in the move-veterans-for-picks mode yet. That said, if he were - and I think he should be looking at this option - the one good thing going for us is that that 3 of the teams in the top 5 - Tampa, Nashville, and Carolina - aren't really in full "rebuild" mode and so may be more willing to move a high pick for an immediate need. Tampa for sure needs to get back to the playoffs, given St. Louis' age. Carolina gave up youth and draft picks for Jordan Staal and signed Semin to a big deal, which indicates they aren't looking to rebuild slowly. Nashville seems to always be in "win now" mode though they may be the least likely of the 3 to deal a pick.
Based on that, I'd really want Gillis to explore what ONE of Edler, Kesler, or Schneider bring you back from one of these teams. Obviously we'd want the most for Kesler, but both he and Edler are players who I think have reputations that outpace their actual contributions the last few years, while Schneider is my preferred goalie but at this point I think we could do fine with Luongo until Lack develops. And timing wise, a player like McKinnon, Drouin, or Barkov would probably need to develop for another year and then be ready to step into a key role in 2014 when the Sedins contract is up and this team is needing to re-tool. As far as succession planning goes, it makes a lot of sense. Sadly, in a "win now" market like Vancouver (and Toronto), GMs never have the patience to take a step back in order to take two steps forward. At least until they are forced to, a la Calgary ...