He is going to be in a tough spot. Datsyuk, Zetterberg, Nyquist, Franzen and Alfie if he returns have 5 of the top 6 locked down. That leaves Weiss having to slug it out with Tatar and Abdelkader for the last spot. If Babcock puts Datsyuk and Zetterberg together Weiss may get the 2nd line spot purely because he is a natural center, but if Z and D are split up, I expect Weiss to pull what will effectively be 4th line duty behind Helm.
I would imagine an all-healthy roster to look something like:
Top 6: Datsyuk, Zetterberg, Alfie, Nyquist, Franzen, Abdelkader
3rd line: Helm, Tatar, Weiss (if he can play on the wing)
4th line: Anderson, Miller, Sheahan
Again if Z and D play together, I could see Weiss swap into the top 6 with Abby to take the 2nd line C position and abby going to 3rd line with Tatar and Helm.