In what way? Most of the film focuses on Fassbender and questions regarding life. That's right in the posthuman wheelhouse.
Most of the film doesn't.
The part that does is enjoyable. But you're leaving out the vast majority of the movie.
The part involving a barely competent starship crew with forced banter trying to escape disaster is reminiscent of Alien: Resurrection.
The part involving a hidden conspiracy among crew members (e.g. Theron and Pierce) is reminiscent of Alien: Resurrection (e.g. Ryder).
The part involving hubris from experimentation on life forms they don't really understand is reminiscent of Alien: Resurrection.
The part involving humans changing in personality after being infected with alien contaminants is reminiscent of Alien: Resurrection.
Ultimately, the movie tried to handle too many different (and competing) plot threads and it buckled and collapsed under the strain.
Blade Runner may be my favourite movie. I have a framed movie poster in my basement. Prometheus did not remind me of Blade Runner. Some of the themes may be similar, but there are light-years of difference in the execution.
Blade Runner explored them through slow, careful character exploration and a modest plot and setting with noir sensibilities.
Prometheus went full sci-fi action epic with grand notions of the source of humanity.