Just some 'recent' trades to use as a barometer:
2011: Anaheim traded #22 to Toronto for #30 and #39
2009: Columbus traded #16 and #77 to NY Islanders for #26, #37, #62, #92 -- This one was peculiar in that it was done before the draft began. Columbus then scrambled to trade back up to #21.
2007: Phoenix traded #21 to Edmonton for #30 and #36
It's tough to say since it'll depend on a team's draft board. But yeah, I would expect Ottawa to be fairly active with their picks but moving up 10+ spots in the first round is usually a tough proposition. Something smaller like #33 + one of their late 2nds or early 3rds to get back in at the tail end of the first might be more likely.