I could think goon-culture could come back, because nowadays they now know better about the concussions. And doctors can treat them better, so people won't go to self-treatreatmet with wrong medicines etc.
IMO, the concussion/long term health narrative is what will keep it from really making a comeback. That and all the latest rule changes that help deter it (instigator, helmet removal, mandatory visors, junior limits, etc. etc.).
Most of that was probably strengthened after the last time fighting made a "comeback". Fighting dropped pretty heavily after the lockout, until the Ducks gooned their way to the 2007 Cup. Made perfect sense then, when you could send out and sacrifice Brad May for the tail end of his 5 minutes of ice time and have him sucker punch and take out the other teams best dman. Or have your two best Dmen team up to slam a guys head into the glass and only lose one for a game. The rest of the league decided to follow suit, including the Red Wings. But at that point, the league and media hadn't yet perfected the notion that every fighter was one punch or one concussion away from having a miserable post hockey existence that will end tragically maybe even at their own hand.
The way I see it going forward, is guys like Tom Wilson, Zach Kassian, Wayne Simmonds, etc. etc. having the same ire as enforcers once did. That or having the role bestowed upon lighter weight 4th line/3rd pairing guys that can skate/kill penalities/etc. Kind of like when the Red Wings had McCarty handle the enforcer role when Kocur was injured and eventually retired.
The days of guys like John Scott, Boogaard, Twist, etc etc being on rosters as a one trick pony are probably over for good.