Yeah, it's too bad but Isco won't be going anywhere. I still would prefer to see him on a team built around him (like I would most superstars as opposed to having them all concentrated on one or two teams) but he's starting to really come into his own and he'll win a ton of trophies at Madrid.
More on that note...I really would like to see a few more ambitious elite players who would prefer to carry a team as opposed to just make the biggest move to the team most likely to win trophies even without them. Neymar, Isco, Bale to an extent, Suarez, etc. Like the top attacking talents in the world don't all have to be on the same team. It's why I hope Hazard does stay at Chelsea and I'm happy Griezmann is staying with Atletico, and I hope Dybala stays with Juve. I think you'll see James really step up his output and get a bit more recognition again once he moves away from Madrid.