Early in the 1st, DeBrusk skated in towards the boards to stick check a Cane but tripped over the back of the Cane's skate and went shoulder first into the boards. His head probably clipped the dasher slightly as his helmet was tipped but he got up hunched over as if it was his shoulder. With 16 minutes left in the 3rd, he dove to try to put the puck in the net and rolled slowly into the boards. They showed him grimacing on the bench.
With about 2:40 (or maybe 2:20) to go in the 2nd, Krug was skating forward entering his defensive zone slightly ahead of the Canes puck carrier who stopped just over the blue line. Krug attempted to stop and it looked like he stretched a leg out awkwardly. He played another shift before the end of the 2nd. I'd guess groin strain. He started the 3rd and had 1 shift after the Canes went up 4-1.
Krug and DeBrusk both went off during the 13:20ish commercial break in the 3rd.
Chara was on ice to start returning from that 13:20 break. Went down parallel to the boards twice on that shift but got right up. Nothing looked out of place. He left at the next stoppage at about 11:20.