Anxiety, depression, addictive behavior, drug and alcohol abuse are all symptomatic of CTE. You can't really separate Rypien's CTE from his mental health issues.
Just to put some perhaps familiar names to the symptoms. Of course there are many hockey players and people from all walks of life who have had many of or all of these symptoms (well suicide is not really a symptom - it's pretty final) but were not NHL enforcers. However the numbers and the connection are becoming hard to deny.
Suicides:
- Rick Rypien
- Derek Boogaard
- Wade Belakk
- Todd Ewen
- Steve Montador
- Trevor Ettinger
- Marc Potvin
Drugs, Alcohol and addictions
- Bob Probert
- Stu Grimson
- Brantt Myhres
- Todd Fedoruk
- Darren McCarty
- Ken Daneyko
- John Kordic
One of the links to drug abuse is addition to opioids and other pain killers that pretty much all enforcers take regularly and in increasingly large doses as they require more and more to deal with the constant pain.
Depression
- Rich Clune
- Gino Odjick
- Stephen Peat
Additionally Corey Hirsch has talked about his struggles with anxiety, OCD and depression. He was not a fighter, but as a goalie he had multiple concussions.
Then there is the NFL were the league settled with over 4500 former players. Studies cited in the case linked concussions and CTE to depression, anxiety, additions, and neurodegenerative disorders such as ALS and Alzheimers.