wheeler and scheifele are great at puck possession, so I dont want both of them on the same line.
Ehlers and laine both have good shooting skills so I dont want them on the same line.
pereault and little are great playmakers but lack size and strength so they should be on a line that have a good shooter and a good puck possession player, this way as soon as the puck is on the stick of little/pereault, they have two options to go to, the shooter or the puck possession artist.
Laine/ehlers are good shooters, but they need players that can pass them the puck, and thats what puck possession players and playmakers are for.
wheeler/scheifele are strong and can hold the puck but you cant expect them to hold it forever, so you need to provide them with good shooters and playmakers.
so I would go with,
pereault scheifele laine
ehlers little wheeler