OT: 83rd Obsequious Banter Thread: Balls to the Wall

Discussion in 'Philadelphia Flyers' started by MiamiScreamingEagles, May 20, 2021.

  1. Lord Defect Secretary of Blowtorching

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    That’s my view on pulled pork vs brisket as well. Brisket is in another league.
     
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  2. Beef Invictus Meat Overlord

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  3. Captain Dave Poulin Imaginary Cat

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    I can put a few dozen hot dogs on a few dozen pieces of bread, but that doesn't mean that I have a few dozen sandwiches.

    Also, hot dogs >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> steak.
     
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  4. DancingPanther Sco Plats Sponsor

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    I know nothing of this. Standby
     
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  5. Embiid 21=The # of the Embeast!

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    I think even the slowing is negligible but have to research more....

     
  6. DancingPanther Sco Plats Sponsor

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    Wrong.

    @Beef Invictus

    The issue is the slowing is all theoretical, and because it's theoretical and not proven, some people are butthurt.

    There are no drugs that treat the disease, only the symptoms. There are meds out there that preserve memory by only months, and they're approved. Everything approved now only slows the progression. Alzheimer's has been widely HYPOTHESIZED to be caused by the buildup of amyloid beta in the brain. This drug was tested on people with Alzheimer's who didn't show any statistically significant improvement.

    However, since it's been proven to combat the buildup of amyloid beta, it was approved by the FDA on those grounds; on the hypothesis that it could work in very early stage Alzheimer's, for example.

    But some experts are arguing you can't act on what is essentially a hunch- that it's not how the process works. Which, honestly they're right. But, since it's also been proven safe, if you want my opinion I say go for it. This is an orphan drug so it got fast tracked (orphan drugs are special because they're for rare conditons or curative therapies for those with no known cure) so let's see how it works post-hoc.
     
    Last edited: Jun 10, 2021
  7. Embiid 21=The # of the Embeast!

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    "This drug was tested on people with Alzheimer's who didn't show any statistically significant improvement."

    RIGHT...so it is negligible or better yet inconclusive results thus far....
     
  8. Beef Invictus Meat Overlord

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    OK, this is exactly what if felt like. People being butthurt that it isn't blindly following the book, despite there being really no downside.
     
  9. DancingPanther Sco Plats Sponsor

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    I didn't read the actual study but yeah that's the gyst of it

    I'm usually of the science book too but you gotta start somewhere, why not here? That's just my thought anyway
     
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  10. Embiid 21=The # of the Embeast!

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    I don't see it that harshly....I think critics have some fair points as well. Here is a good story about the controversy

    Why the FDA approved a controversial Alzheimer’s drug | PBS NewsHour
     
  11. trostol By Grabthar's hammer... what a savings.

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    Lupin returns at 3 am...weeeeeee
     
  12. ajgoal Almost always never serious

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    So the drug is safe? That should be all the criteria the FDA needs to approve. Beyond that should be between the doctor and the patient.
     
  13. Embiid 21=The # of the Embeast!

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    Don Nachbaur 26 likes this.
  14. Embiid 21=The # of the Embeast!

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    The issue is that they had all of two clinical trials one of which showed some benefit and another that showed no benefit at all. So it is not conclusive that the drug is safe or effective for that matter. If you read the transcript of the interview I posted or listen to it this is a key part...

    And as far as between the doc and patient more like between the doc and pharma rep...lol
    So the cost benefit analysis will really be done in the next 3-5 years...hopefully not too many people will be "butthurt"...

     
    Last edited: Jun 11, 2021
  15. Embiid 21=The # of the Embeast!

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  16. Jack Straw Moving much too slow Sponsor

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  17. Tripod Registered User

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    Hope some of you are watching the Frech Open. Fantastic tennis between Nadal and Joker
     
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  18. Hollywood Couturier Shakira Stan

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  19. Beef Invictus Meat Overlord

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    Tennis is dogwater.
     
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  20. Tripod Registered User

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    Beef Invictus is boiled hot dog water

    wait....would that make it soup?
     
  21. CanadianFlyer88 Knublin' PPs

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    Wondered if you could ever top some of your awful food takes.

    And, there it is. /Goldblum
     
  22. Jack Straw Moving much too slow Sponsor

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    I don't know about you but my dogs drink the same water that I do. And it's good water.
     
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  23. Beef Invictus Meat Overlord

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    Yes
     
  24. Beef Invictus Meat Overlord

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    It's a broth
     
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  25. Tripod Registered User

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    I see someone is responding to their own posts again...
     

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