Discussion in 'Philadelphia Flyers' started by MiamiScreamingEagles, May 20, 2021.
That’s my view on pulled pork vs brisket as well. Brisket is in another league.
OK, I'm not informed here. What I've read/heard, the problem is that it merely slows progression instead of reversing it.
What's the problem with that?
@DancingPanther come enlighten me
I can put a few dozen hot dogs on a few dozen pieces of bread, but that doesn't mean that I have a few dozen sandwiches.
Also, hot dogs >>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>>> steak.
I know nothing of this. Standby
I think even the slowing is negligible but have to research more....
The issue is the slowing is all theoretical, and because it's theoretical and not proven, some people are butthurt.
There are no drugs that treat the disease, only the symptoms. There are meds out there that preserve memory by only months, and they're approved. Everything approved now only slows the progression. Alzheimer's has been widely HYPOTHESIZED to be caused by the buildup of amyloid beta in the brain. This drug was tested on people with Alzheimer's who didn't show any statistically significant improvement.
However, since it's been proven to combat the buildup of amyloid beta, it was approved by the FDA on those grounds; on the hypothesis that it could work in very early stage Alzheimer's, for example.
But some experts are arguing you can't act on what is essentially a hunch- that it's not how the process works. Which, honestly they're right. But, since it's also been proven safe, if you want my opinion I say go for it. This is an orphan drug so it got fast tracked (orphan drugs are special because they're for rare conditons or curative therapies for those with no known cure) so let's see how it works post-hoc.
"This drug was tested on people with Alzheimer's who didn't show any statistically significant improvement."
RIGHT...so it is negligible or better yet inconclusive results thus far....
OK, this is exactly what if felt like. People being butthurt that it isn't blindly following the book, despite there being really no downside.
I didn't read the actual study but yeah that's the gyst of it
I'm usually of the science book too but you gotta start somewhere, why not here? That's just my thought anyway
I don't see it that harshly....I think critics have some fair points as well. Here is a good story about the controversy
Why the FDA approved a controversial Alzheimer’s drug | PBS NewsHour
Lupin returns at 3 am...weeeeeee
So the drug is safe? That should be all the criteria the FDA needs to approve. Beyond that should be between the doctor and the patient.
Fewer Young Men Are in the Labor Force. More Are Living at Home
Bloomberg - Are you a robot?
The issue is that they had all of two clinical trials one of which showed some benefit and another that showed no benefit at all. So it is not conclusive that the drug is safe or effective for that matter. If you read the transcript of the interview I posted or listen to it this is a key part...
And as far as between the doc and patient more like between the doc and pharma rep...lol
So the cost benefit analysis will really be done in the next 3-5 years...hopefully not too many people will be "butthurt"...
High noon erection
Jeff Bezos' space mission ridiculed after rocket likened to giant todger
Hope some of you are watching the Frech Open. Fantastic tennis between Nadal and Joker
Tennis is dogwater.
Beef Invictus is boiled hot dog water
wait....would that make it soup?
Wondered if you could ever top some of your awful food takes.
And, there it is. /Goldblum
I don't know about you but my dogs drink the same water that I do. And it's good water.
It's a broth
I see someone is responding to their own posts again...
Separate names with a comma.