Easily TM's biggest failure as a GM. Everyone knew going into this year that one or two injuries on defense--and let's be real, with Bogosian, losing one defenseman for an extended period of time was more or less guaranteed--would create major problems, and he decided going with Franson as the #6 to start the season wasn't an issue (though he has looked better as of late). Gorges is garbage, too, Nelson needs some seasoning in Rochester, and Falk is Falk.
This team is just uninspiring to watch. We can't play an effective "grind 'em down" game, nor can we be an opportunistic team that cashes in on prime chances at a higher rate than other teams. Who on this team is a threat to score from a sniping standpoint? RoR? Maybe Moulson? And the D is, as noted above, a mess. Even when Eichel returns, these problems aren't gonna magically go away.
EDIT: Yes, all the injuries hurt, but some of the problems go beyond the individual players that are out. There's only so much RoR and Eichel can do.